Chemical Biology Team
RIKEN Center for Biosystems Dynamics Research (BDR)
Publication
18. “Synthesis of (2,2-Diborylvinyl)arenes by Rhodium-Catalyzed Desulfanylative gem-Diborylation of 2-Arylvinyl Sulfides”
Yuta Uetake, Motoyuki Isoda, Takashi Niwa*, Takamitsu Hosoya*
Org. Lett. 2019, in press. DOI:10.1021/acs.orglett.9b01253
* * *
17. “Divergent synthesis of photoaffinity probe candidates by click reactions of azido-substituted aryltrifluoromethyldiazirines”
Kenji Watanabe, Junpei Tsuda, Hidenori Ochiai, Takashi Niwa, Takamitsu Hosoya*
Heterocycles. 2019, 99, 1366–1387. DOI:10.3987/COM-18-S(F)76
16. “Association between aromatase in human brains and personality traits”
Kayo Takahashi, Takamitsu Hosoya, Kayo Onoe, Tadayuki Takashima, Masaaki Tanaka, Akira Ishii, Yasuhito Nakatomi, Shusaku Tazawa, Kazuhiro Takahashi1, Hisashi Doi, YasuhiroWada Yasuyoshi Watanabe*
Sci. Rep 2018, 8, 16841. DOI:10.1038/s41598-018-35065-4
15. “Palladium(II)-mediated rapid 11C-cyanation of (hetero)arylborons”
Zhouen Zhang, Takashi Niwa, Yasuyoshi Watanabe, Takamitsu Hosoya
Org. Biomol. Chem 2018, 16, 7711–7716. DOI:10.1039/C8OB02049C
14. “Hydrosilyl Group-directed Iridium-catalyzed peri-Selective CH Borylation of Ring-fused (Hetero)Arenes”
Yuto Sumida, Ryu Harada, Tomoe Sumida, Daisuke Hashizume, Takamitsu Hosoya
13. “Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells”
Tomohiro Meguro, Norikazu Terashima, Harumi Ito, Yuka Koike, Isao Kii, Suguru Yoshida* Takamitsu Hosoya*
Chem. Commun., 2018, Advanced Article.
12. “Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ”
Isao Kii∗, Shino Hirahara-Owada, Masataka Yamaguchi, Takashi Niwa, Yuka Koike, Rie Sonamoto, Harumi Ito, Kayo Takahashi, Chihiro Yokoyama, Takuya Hayashi, Takamitsu Hosoya, Yasuyoshi Watanabe
Anal. Biochem. 2018, 549, 174–183.
11. “Copper-Catalyzed Regioselective Monofluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes”
Hironobu Sakaguchiª, Yuta Uetakeª Masato Ohashi, Takashi Niwa*, Sensuke Ogoshi*, Takamitsu Hosoya*
(ª H.S. and Y.U. contributed equally.）
J. Am. Chem. Soc. 2017, 139, 12855–12862.
DOI: 10.1021/jacs.7b08343
10. “A study on an unusual SN2 mechanism in the methylation of benzyne through nickel-complexation”
Makoto Hatakeyama,* Yuki Sakamoto, Koji Ogata, Yuto Sumida, Tomoe Sumida, Takamitsu Hosoya, Shinichiro Nakamura*
Phys. Chem. Phys. Chem. 2017, 19, 26926–26933.
9. “Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice”
Akiko Nakano-Kobayashi, Tomonari Awaya, Isao Kii, Yuto Sumida, Yukiko Okuno, Suguru Yoshida, Tomoe Sumida, Haruhisa Inoue, Takamitsu Hosoya, Masatoshi Hagiwara*
8.“Nickel-Catalyzed Reductive Cross-Coupling of Aryl Triflates and Nonaflates with Alkyl Iodides” (invited paper)
Yuto Sumida*, Tomoe Sumida, Takamitsu Hosoya*,
Synthesis 2017, Special Topic in press.
7.“Facile Transformation of α,β-Unsaturated Carboxylic Acids to Alkenylboronic Esters via Rhodium-Catalyzed Decarbonylative Borylation of α,β-Unsaturated Thioesters”
Takashi Niwa,* Hidenori Ochiai, Motoyuki Isoda, Takamitsu Hosoya*
Chem. Lett. 2017, in press. DOI:10.1246/cl.170549
6.“Copper-Catalyzed ipso-Borylation of Fluoroarenes”
Takashi Niwa,* Hidenori Ochiai, Takamitsu Hosoya*
ACS Catal. 2017, 7, 4535–4541. DOI: 10.1021/acscatal.7b01448
5.“Rhodium-Catalyzed Decarbonylative Borylation of Aromatic Thioesters for Facile Diversification of Aromatic Carboxylic Acids”
Hidenori Ochiai, Yuta Uetake, Takashi Niwa*, Takamitsu Hosoya*,
Angew. Chem., Int. Ed. 2017, 56, 2482–2486. DOI: 10.1002/anie.201611974
4.“Stereoinversion of Stereocongested Carbocyclic Alcohols via Triflylation and Subsequent Treatment with Aqueous N,N-Dimethylformamide”
Hidenori Ochiai, Takashi Niwa, Takamitsu Hosoya*,
Org. Lett. 2016, 18, 5982–5985. DOI: 10.1021/acs.orglett.6b02675
3.“Preparation of Aryne−Nickel Complexes from ortho-Borylaryl Triflates”
Yuto Sumida, Tomoe Sumida, Daisuke Hashizume, Takamitsu Hosoya*
Org. Lett. 2016, 18, 5600–5603. DOI: 10.1021/acs.orglett.6b02831
2.“Rhodium-Catalyzed ispo-Borylation of Alkylthioarenes via C–S Bond Cleavage”
Yuta Uetake, Takashi Niwa, Takamitsu Hosoya*
Org. Lett. 2016, 18, 2758–2761. DOI: 10.1021/acs.orglett.6b01250.
1.“Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C–F Bond Functionalization”
Takashi Niwa,* Hidenori Ochiai, Yasuyoshi Watanabe, Takamitsu Hosoya*
J. Am. Chem. Soc. 2015, 137, 14313–14318.
[Most Read Article in Nov.–Dec.., 2015, highest ranking: 6th at Dec. 2, 2015.]
Review
1.“Novel Methods for Efficient Conjugation of Two Azide Molecules”
Suguru Yoshida, Isao Kii, Takamitsu Hosoya
J. Synth. Org. Chem. 2016, 74, 453–461.