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       理化学研究所  ライフサイエンス技術基盤研究センター

     分子標的化学研究チーム

     RIKEN Center for Life Science Technologies (CLST)

      Chemical Biology Team

論 文 リ ス ト (2017年11月現在)

丹羽 節

 

Original papers:

22. “Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ” 

Isao Kii*, Shino Hirahara-Owada, Masataka Yamaguchi, Takashi Niwa, Yuka Koike, Rie Sonamoto, Harumi Ito, Kayo Takahashi, Chihiro Yokoyama, Takuya Hayashi, Takamitsu Hosoya, Yasuyoshi Watanabe

Anal. Biochem. 2018, 549, 174–183.

DOI: 10.1016/j.ab.2018.04.001

21. “Copper-Catalyzed Regioselective Monofluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes” 

Hironobu Sakaguchiª, Yuta Uetakeª Masato Ohashi, Takashi Niwa*, Sensuke Ogoshi*, Takamitsu Hosoya*

(ª H.S. and Y.U. contributed equally.)

J. Am. Chem. Soc. 2017, 139, 12855–12862.

DOI: 10.1021/jacs.7b08343

 

 

 

20. 

“Facile Transformation of α,β-Unsaturated Carboxylic Acids to Alkenylboronic Esters via Rhodium-Catalyzed Decarbonylative Borylation of α,β-Unsaturated Thioesters”

Takashi Niwa,* Hidenori Ochiai, Motoyuki Isoda, Takamitsu Hosoya*

Chem. Lett. 2017, 46, 1315–1318.

DOI: 10.1246/cl.170549

[Selected as Editor's Choice]

 

 

19. 

“Copper-Catalyzed ipso-Borylation of Fluoroarenes”

Takashi Niwa,* Hidenori Ochiai, Takamitsu Hosoya*

ACS Catal. 2017, 7, 4535–4541.

DOI: 10.1021/acscatal.7b01448

[Most Read Article in Jun.–Jul.., 2017, highest ranking: 2nd at Jul. 3, 2017.]

 

 

 

 

18. 

“Rhodium-Catalyzed Decarbonylative Borylation of Aromatic Thioesters for Facile Diversification of Aromatic Carboxylic Acids”

Hidenori Ochiai, Yuta Uetake, Takashi Niwa,* Takamitsu Hosoya*

Angew. Chem., Int. Ed. 2017, 56, 2482–2486.

DOI: 10.1002/anie.201611974

 

 

 

 

17. 

“Stereoinversion of Stereocongested Carbocyclic Alcohols via Triflylation and Subsequent Treatment with Aqueous N,N-Dimethylformamide”

Hidenori Ochiai, Takashi Niwa, Takamitsu Hosoya*

Org. Lett. 2016, 18, 5982–5985.

DOI: 10.1021/acs.orglett.6b02675

 

 

 

16. 

“Rhodium-Catalyzed ispo-Borylation of Alkylthioarenes via C–S Bond Cleavage”

Yuta Uetake, Takashi Niwa, Takamitsu Hosoya*

Org. Lett. 2016, 18, 2758–2761.

DOI: 10.1021/acs.orglett.6b01250

 

 

 

15. 

“Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C–F Bond Functionalization”

Takashi Niwa,* Hidenori Ochiai, Yasuyoshi Watanabe, Takamitsu Hosoya*

J. Am. Chem. Soc. 2015, 137, 14313–14318.

[Most Read Article in Nov.–Dec.., 2015, highest ranking: 6th at Dec. 2, 2015.]

DOI: 10.1021/jacs.5b10119

 

 

 

14. 

"Highly enantioselective catalytic asymmetric Mukaiyama–Michael reactions of cyclic α-alkylidene β-oxo imides"

Harufumi Oyama, Kohei Orimoto, Takashi Niwa, Masahisa Nakada

Tetrahedron Asymmetry 2015, 26, 262–270.

DOI:10.1016/j.tetasy.2015.01.012

 

 

 

13. 

"Synthesis and characterization of a new C2-symmetrical chiral tridentate N-heterocyclic carbene ligand coordinated Cr(III) complex"

Yuta Uetake, Takashi Niwa, Masahisa Nakada

Tetrahedron Asymmetry 2015, 26, 158–162.

DOI:10.1016/j.tetasy.2015.01.003.

 

 

 

12. 

“Synthesis of cycloalkanone-fused cyclopropanes by Au(I)-catalyzed oxidative ene-yne cyclizations"

Yuta Uetake, Takashi Niwa, Masahisa Nakada

Tetrahedron Lett. 2014, 55, 6847–6850.

DOI:10.1016/j.tetlet.2014.10.084.

 

 

 

11.

“Preparations of Imides via the Palladium-Catalyzed Coupling Reaction of Organostannanes with Methyl N-[Methoxy(methylthio)methylene]carbamate”

Kohei Orimoto, Takuhei Tomizawa, Yuki Namera, Harufumi Oyama, Takashi Niwa and Masahisa Nakada

Heterocycles 2013, 87, 827–840. 

DOI: 10.3987/COM-13-12662

 

 

 

10.

“Catalytic Asymmetric [4+2] Cycloadditions and Hosomi–Sakurai Reactions of α-Alkylidene β-Keto Imides”

Kohei Orimoto, Harufumi Oyama, Yuki Namera, Takashi Niwa and Masahisa Nakada

Org. Lett. 2013, 15, 768–771. 

DOI: 10.1021/ol303381c

 

 

 

9.

“Preparation of Imides via the Palladium-Catalyzed Coupling Reaction of Organoborons with Methyl N-[Methoxy(methylthio)methylene]carbamate as a One-Carbon Elongation Reaction”

Takuhei Tomizawa, Kohei Orimoto, Takashi Niwa and Masahisa Nakada

Org. Lett. 2012, 14, 6294–6297. 

DOI: 10.1021/ol303062a

 

 

 

8.

“A Non-Heme Iron(III) Complex with Porphyrin-like Properties That Catalyzes Asymmetric Epoxidation”

Takashi Niwa* and Masahisa Nakada*

J. Am. Chem. Soc. 2012, 134, 13538–13541.

[Most Read Article in August 2012. Highlighted in SYNFACTS 2012, 8, 1219.]

DOI: 10.1021/ja304219s

 

 

 

7.“Pd-Catalyzed reductive cleavage of alkyl aryl sulfides with triethylsilane that is accelerated by trialkylsilyl chloride”

Takehiko Matsumura, Takashi Niwa, and Masahisa Nakada

Tetrahedron Lett. 2012, 53, 4313–4316.

DOI: 10.1016/j.tetlet.2012.06.002

 

 

 

6.

“Palladium-Catalyzed (N-Oxido-2-pyridinyl)methyl Transfer from 2-(2-Hydroxyalkyl)pyridine N-Oxide to Aryl Halides by β-Carbon Elimination”

Takafumi Suehiro, Takashi Niwa, Hideki Yorimitsu, and Koichiro Oshima

Chem. Asian J. 2009, 4, 1217–1220.

DOI: 10.1002/asia.200900151

 

 

 

5.

“Carbon–Carbon Bond Formations at the Benzylic Positions of N-Benzylxanthone and N-Benzyldi-1-naphthyl Ketone Imine”

Takashi Niwa, Takafumi Suehiro, Hideki Yorimitsu, and Koichiro Oshima

Tetrahedron 2009, 65, 5125–5131.

DOI: 10.1016/j.tet.2009.02.034

 

 

 

4.

“Palladium-Catalyzed Benzylic Direct Arylation of Benzyl Sulfone”

Takashi Niwa, Hideki Yorimitsu, and Koichiro Oshima

Tetrahedron 2009, 65, 1971–1976.

DOI: 10.1016/j.tet.2009.01.030

 

 

 

3.

“Palladium-Catalyzed Benzylic Arylation of N-Benzylxanthone Imine”

Takashi Niwa, Hideki Yorimitsu, and Koichiro Oshima

Org. Lett. 2008, 10, 4689–4691.

DOI: 10.1021/ol802070d

 

 

 

2.

“Palladium-Catalyzed Direct Arylation of Aryl(azaaryl)methanes with Aryl Halides Providing Triarylmethanes”

Takashi Niwa, Hideki Yorimitsu, and Koichiro Oshima

Org. Lett. 2007, 9, 2373–2375.

DOI: 10.1021/ol0708119

 

 

 

1. “Palladium-Catalyzed 2-Pyridylmethyl Transfer from 2-(2-Pyridyl)ethanol Derivatives to Organic Halides by Chelation-Assisted Cleavage of Unstrained sp3C–sp3C Bonds”

Takashi Niwa, Hideki Yorimitsu, and Koichiro Oshima

Angew. Chem. Int. Ed. 2007, 46, 2643–2645.

DOI: 10.1002/anie.200604472

 

 

 

 

Reviews:

 

6. 「医薬品をPETプローブに作り変える分子リノベーション技術の開発」丹羽節

アイソトープニュース, 2017, 753 (10), 8–13.

5. 「低分子PETプローブの開発」丹羽節, 細谷孝充

日本レーザー医学会誌, 2017, 37 (4), 465–472.

4. 「[18F]トリフルオロメチル化:1つだけ異なるフッ素を導入する方法」丹羽節

ファルマシア((財)日本薬学会、トピックス), 2014, 50 (7), 691.

3. 「メタノールを有機化学の材料に」丹羽節

化学((株)化学同人、Review of Chemistry in 2011、注目の論文), 2011, 66 (8), 64–65.

2. 「可視光で励起する遷移金属錯体を用いた有機合成反応」丹羽節

有機合成化学協会誌(Review de Debut), 2010, 68 (12), 1307-1308.

1. 「ハーバード大学(Ritter研)での留学生活」丹羽節

OM News(近畿化学協会編、海外研究室レポート), 2010 (2), 50-51.

 

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